FOR IMMEDIATE RELEASE
Tara DiMilia, 908-947-0500, [email protected]
Grants are designed to inspire new research to deal with the challenges of Lyme disease
PORTOLA VALLEY, Calif., January 15, 2019—Bay Area Lyme Foundation, a number one sponsor of Lyme illness research in the US, is saying a call for entries for their 2019 Emerging Leader Awards (ELA), that are designed to encourage promising scientists who embody the way forward for Lyme illness analysis leadership in the US. This yr, two $100,000 grants shall be awarded in Might. Recipients might be researchers from academia or the personal sector who’re at present at the post-doctoral via the assistant professor degree or equivalent, and who have demonstrated skilled and scientific management in the biomedical sciences. They should have a defined strategy that gives scientific rationale for a analysis challenge that can advance diagnostics or remedies for Lyme illness. Proof of idea for the $100,000 awards must be feasible in 12–18 months.
These awards, together with different Bay Area Lyme Foundation efforts, goal to fill a niche as the National Institutes of Well being (NIH) funding for Lyme disease research is inadequate. While there are almost 10 occasions as many individuals recognized annually with Lyme than HIV in the US, Lyme illness receives roughly 1% of the public funding that is allocated for HIV/AIDS.
“While Lyme is one of the fastest-growing infectious diseases in the country, with 427,430 new cases reported in the US alone in 2017, Lyme research is dramatically underfunded,” stated Bonnie Crater, chairperson, science committee, Bay Area Lyme Foundation. “Our hope is that these awards will aid in transforming the research landscape by providing the funds necessary to spur incentive for researchers to consider novel approaches to produce reliable diagnostics, and treatments that work.”
The Emerging Leader Award grant is designed to be a catalyst for future research. Lots of the ELA winners have gone on to obtain grants from other groups together with the NIH, as well as continued help from Bay Area Lyme Foundation and its research companions.
Previous ELA recipients have come from institutions together with Brandeis College, Harvard College/Massachusetts Institute of Know-how, Infectious Illnesses Diagnostic Laboratory at Boston Youngsters’s Hospital, Louisiana State College, North Carolina State University, Stanford University Faculty of Drugs, and University of California, San Francisco, Wyss Institute.
Most of those tasks have been in the early levels of analysis upon submission for consideration, and the Emerging Leader Award provided a springboard for scientists to explore the concepts that have been later acknowledged with grants from the government and other established entities, growing the scope of investigation in Lyme illness.
Previous Emerging Leader Award recipients embrace:
- George Church, PhD, professor of genetics at Harvard Medical Faculty, professor of well being sciences and know-how at Harvard and the Massachusetts Institute of Know-how (MIT). He was awarded the Emerging Leader Award in 2018 to launch the Genomic Lyme Disease Research Initiative venture at Harvard Medical Faculty. Via this initiative, he and Dr. Wu hope to raised perceive not provided that some individuals are more prone to the disease, but in addition if those that are exceptionally less prone might supply clues that time toward potential therapeutic research.
- Ting Wu, PhD, professor of genetics at Harvard Medical Faculty, director of the Consortium for Area Genetics, and director of the Personal Genetics Schooling Challenge. She was awarded the Emerging Leader Award in 2018 to launch the Genomic Lyme Illness Research Initiative venture at Harvard Medical Faculty. By way of this initiative, she and Dr. Church plan to match the genetic and immune variations of those that have Lyme illness with those who are unaffected, in an effort to raised perceive the genetic underpinnings of the disease as well as discovering targets for future therapeutics.
- Michal Caspi Tai, PhD, a postdoctoral analysis fellow in the lab of Irving Weissman at Stanford College, is understood for her work exploring immune response in continual an infection. She is going to research the micro organism’s capacity to utilize the CD47 immune escape mechanism which has been noticed in different infectious illnesses as well as most cancers. This understanding might result in advances in remedy.
- Steven E. Phillips, MD, a Yale-educated, world-renowned clinician who focuses on treating persistent tick-borne infections together with Lyme disease and bartonellosis, will carry out initial testing of a novel therapeutic technique aimed toward more effectively eliminating difficult-to-treat tick-borne illnesses, based mostly on robust proof that persistent pathogens can evade the current therapies.
- James J. Collins, PhD, core school Wyss Institute, Harvard University; Termeer professor of medical engineering & science; professor, Massachusetts Institute of Know-how (MIT). Dr. Collins’ work centers around synthetic biology and methods biology, with a specific give attention to using network biology approaches to review antibiotic action, bacterial defense mechanisms, and the emergence of resistance. Dr. Collins was awarded the Emerging Leader Award in 2017 to analysis a direct detection RNA diagnostic for early Lyme disease.
- Yuko Nakajima, PhD, postdoctoral fellow Brandeis College. Dr. Nakajima is presently a postdoctoral fellow in the lab of James E. Haber at Brandeis. Dr. Nakajima acquired the Emerging Leader Award in 2017 to research potential remedies to dam immune evasion by the micro organism causing Lyme illness. Previous to beginning her Borrelia burgdorferi research, her work investigated the relationship between DNA injury and spindle assembly checkpoints throughout cell division.
- Britton J. Grasperge, PhD, Brandeis University Louisiana State University. Dr. Grasperge is working to determine substances within tick saliva which are responsible for attracting the micro organism that causes Lyme disease in an effort to develop a better diagnostic.
- Chase Beisel, PhD, assistant professor, North Carolina State University. Dr. Beisel is exploring the potential means of CRISPR-Cas genome concentrating on to kill the micro organism that causes Lyme.
- Lisa Okay. Blum, PhD, postdoctoral fellow, Stanford University Faculty of Drugs. Dr. Blum is researching an immune response to Lyme illness that has the potential to assist elucidate why some individuals have short-term symptoms from a Lyme infection and why others develop into chronically ailing, as well as the hope of leading to the improvement of an improved diagnostic and/or therapeutic.
- Jerome F. M. Bouquet, PhD, postdoctoral fellow, College of California, San Francisco. Dr. Bouquet is researching potential “biomarkers” that may permit for the improvement of a medical diagnostic for each acute and post-treatment Lyme disease.
- John Branda, MD, assistant professor, Harvard Medical Faculty and assistant pathologist, Massachusetts Common Hospital (MGH). Dr. Branda’s research focuses on enhancing patient care by means of the improvement of latest diagnostic strategies and the optimization of laboratory checks and antimicrobial agents, together with tick-borne sicknesses reminiscent of Lyme borreliosis, anaplasmosis, and tularemia.
- Nira Pollack, MD, PhD, assistant professor, Harvard Medical Faculty, and affiliate medical director of the Infectious Illnesses Diagnostic Laboratory at Boston Youngsters’s Hospital. Dr. Pollock’s research has a special interest in the improvement and analysis of novel diagnostic exams for infectious illnesses and related purposes. Her Lyme-related work has included the discovery of novel biomarkers of early Lyme borreliosis.
Purposes can be accepted from researchers all through the United States via March 1, 2019. Applicants must submit an software, research proposal, and a minimum of one supporting letter from their supervising supervisor or Principal Investigator. Bulletins of Awards can be made during Bay Area Lyme Foundation’s annual LymeAid® fundraising event in Might 2019. The complete criteria and software for this award may be found at www.bayarealyme.org/our-research/emerging-leader-award.
About Bay Area Lyme Foundation Emerging Leader Awards
The Emerging Leader Awards from Bay Area Lyme Foundation are made potential annually by beneficiant donations from the LaureL STEM Fund and the Steven & Alexandra Cohen Basis. These awards are introduced yearly and are designed to be awarded to promising scientists who’ve recognized a defined strategy to improved diagnostics or therapies for Lyme illness. Researchers fascinated about making use of for the 2019 Emerging Leader Award or learning about the other grants that Bay Area Lyme Basis provides all through the yr ought to contact [email protected]
About Lyme disease
One among the commonest infectious illnesses in the country, Lyme illness is a probably disabling an infection brought on by bacteria transmitted via the chew of an contaminated tick to individuals and pets. If caught early, most instances of Lyme disease could be successfully treated, but it’s commonly misdiagnosed as a consequence of lack of know-how and unreliable diagnostic checks. There are about 329,000 new instances of Lyme illness annually, in accordance with statistics launched in 2015 by the CDC. And, this number is rising annually as 427,430 new Lyme instances are believed to have occurred in the US alone in 2017. Because of the problem in diagnosing and treating Lyme illness, as many as one million People could also be suffering from the impression of its debilitating long-term symptoms and problems, in line with Bay Area Lyme Foundation estimates.
About Bay Area Lyme Basis
Bay Area Lyme Basis, a nationwide group committed to making Lyme disease straightforward to diagnose and simple to remedy, is the main public not-for-profit sponsor of progressive Lyme illness research in the US. A 501c3 non-profit organization based mostly in Silicon Valley, Bay Area Lyme Basis collaborates with world-class scientists and establishments to speed up medical breakthroughs for Lyme illness. Additionally it is devoted to providing reliable, fact-based info so that prevention and the significance of early remedy are widespread information. A pivotal donation from The LaureL Basis covers overhead prices and permits for 100% of all donor contributions to Bay Area Lyme Basis to go on to research and prevention packages. For extra information about Lyme illness or to become involved, go to www.bayarealyme.org or call us at 650-530-2439.