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Call for Entries for the Bay Area Lyme Foundation’s 2019 Emerging Leader Award Grant

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Tara DiMilia, 908-947-0500, [email protected]

Call for Entries for the Bay Area Lyme Foundation’s 2019 Emerging Leader Award Grant

Grants are designed to inspire new analysis to deal with the challenges of Lyme illness

PORTOLA VALLEY, Calif., January 15, 2019—Bay Area Lyme Foundation, a leading sponsor of Lyme illness research in the US, is saying a name for entries for their 2019 Emerging Leader Awards (ELA), that are designed to encourage promising scientists who embody the future of Lyme illness research management in the US. This yr, two $100,000 grants can be awarded in Might. Recipients will probably be researchers from academia or the personal sector who’re presently at the post-doctoral via the assistant professor degree or equivalent, and who have demonstrated professional and scientific management in the biomedical sciences. They need to have an outlined strategy that gives scientific rationale for a research venture that can advance diagnostics or remedies for Lyme disease. Proof of concept for the $100,000 awards must be feasible in 12–18 months.

These awards, along with other Bay Area Lyme Foundation efforts, purpose to fill a niche as the Nationwide Institutes of Well being (NIH) funding for Lyme illness research is inadequate. While there are almost 10 occasions as many people recognized annually with Lyme than HIV in the US, Lyme disease receives approximately 1% of the public funding that’s allotted for HIV/AIDS.

“While Lyme is one of the fastest-growing infectious diseases in the country, with 427,430 new cases reported in the US alone in 2017, Lyme research is dramatically underfunded,” stated Bonnie Crater, chairperson, science committee, Bay Area Lyme Foundation. “Our hope is that these awards will aid in transforming the research landscape by providing the funds necessary to spur incentive for researchers to consider novel approaches to produce reliable diagnostics, and treatments that work.”

The Emerging Leader Award grant is designed to be a catalyst for future research. Lots of the ELA winners have gone on to obtain grants from different teams together with the NIH, as well as continued help from Bay Area Lyme Basis and its analysis partners.

Past ELA recipients have come from institutions together with Brandeis College, Harvard University/Massachusetts Institute of Know-how, Infectious Illnesses Diagnostic Laboratory at Boston Youngsters’s Hospital, Louisiana State College, North Carolina State University, Stanford College Faculty of Drugs, and University of California, San Francisco, Wyss Institute.

Most of those tasks have been in the early levels of analysis upon submission for consideration, and the Emerging Leader Award provided a springboard for scientists to explore the ideas that have been later recognized with grants from the authorities and different established entities, growing the scope of investigation in Lyme disease.

Previous Emerging Leader Award recipients embrace:

  • George Church, PhD, professor of genetics at Harvard Medical Faculty, professor of well being sciences and know-how at Harvard and the Massachusetts Institute of Know-how (MIT). He was awarded the Emerging Leader Award in 2018 to launch the Genomic Lyme Disease Research Initiative undertaking at Harvard Medical Faculty. By means of this initiative, he and Dr. Wu hope to raised understand not only if some individuals are extra vulnerable to the disease, but in addition if those that are exceptionally less prone might supply clues that point toward potential therapeutic analysis.
  • Ting Wu, PhD, professor of genetics at Harvard Medical Faculty, director of the Consortium for Area Genetics, and director of the Private Genetics Schooling Venture. She was awarded the Emerging Leader Award in 2018 to launch the Genomic Lyme Illness Analysis Initiative venture at Harvard Medical Faculty. By means of this initiative, she and Dr. Church plan to match the genetic and immune variations of those who have Lyme illness with those that are unaffected, in an effort to raised perceive the genetic underpinnings of the disease as well as finding targets for future therapeutics.
  • Michal Caspi Tai, PhD, a postdoctoral research fellow in the lab of Irving Weissman at Stanford College, is understood for her work exploring immune response in continual an infection. She is going to research the micro organism’s potential to make the most of the CD47 immune escape mechanism which has been observed in different infectious illnesses as well as most cancers. This understanding might lead to advances in remedy.
  • Steven E. Phillips, MD, a Yale-educated, world-renowned clinician who focuses on treating continual tick-borne infections including Lyme illness and bartonellosis, will perform initial testing of a novel therapeutic strategy aimed toward more effectively eliminating difficult-to-treat tick-borne illnesses, based mostly on robust evidence that persistent pathogens can evade the current therapies.
  • James J. Collins, PhD, core school Wyss Institute, Harvard University; Termeer professor of medical engineering & science; professor, Massachusetts Institute of Know-how (MIT). Dr. Collins’ work centers around synthetic biology and methods biology, with a specific concentrate on using network biology approaches to review antibiotic motion, bacterial protection mechanisms, and the emergence of resistance. Dr. Collins was awarded the Emerging Leader Award in 2017 to research a direct detection RNA diagnostic for early Lyme disease.
  • Yuko Nakajima, PhD, postdoctoral fellow Brandeis College. Dr. Nakajima is at present a postdoctoral fellow in the lab of James E. Haber at Brandeis. Dr. Nakajima acquired the Emerging Leader Award in 2017 to research potential remedies to dam immune evasion by the bacteria inflicting Lyme illness. Previous to beginning her Borrelia burgdorferi analysis, her work investigated the relationship between DNA injury and spindle meeting checkpoints during cell division.
  • Britton J. Grasperge, PhD, Brandeis University Louisiana State University. Dr. Grasperge is working to determine substances within tick saliva which might be responsible for attracting the micro organism that causes Lyme disease in an effort to develop a better diagnostic.
  • Chase Beisel, PhD, assistant professor, North Carolina State University. Dr. Beisel is exploring the potential capacity of CRISPR-Cas genome concentrating on to kill the bacteria that causes Lyme.
  • Lisa Okay. Blum, PhD, postdoctoral fellow, Stanford College Faculty of Drugs. Dr. Blum is researching an immune response to Lyme disease that has the potential to help elucidate why some individuals have short-term symptoms from a Lyme infection and why others turn out to be chronically ailing, in addition to the hope of leading to the improvement of an improved diagnostic and/or therapeutic.
  • Jerome F. M. Bouquet, PhD, postdoctoral fellow, University of California, San Francisco. Dr. Bouquet is researching potential “biomarkers” that may permit for the improvement of a medical diagnostic for each acute and post-treatment Lyme illness.
  • John Branda, MD, assistant professor, Harvard Medical Faculty and assistant pathologist, Massachusetts Common Hospital (MGH). Dr. Branda’s analysis focuses on enhancing patient care by means of the improvement of latest diagnostic methods and the optimization of laboratory checks and antimicrobial brokers, including tick-borne sicknesses akin to Lyme borreliosis, anaplasmosis, and tularemia.
  • Nira Pollack, MD, PhD, assistant professor, Harvard Medical Faculty, and associate medical director of the Infectious Illnesses Diagnostic Laboratory at Boston Youngsters’s Hospital. Dr. Pollock’s analysis has a particular curiosity in the improvement and evaluation of novel diagnostic checks for infectious illnesses and associated purposes. Her Lyme-related work has included the discovery of novel biomarkers of early Lyme borreliosis.

Purposes shall be accepted from researchers all through the United States by means of March 1, 2019. Applicants should submit an software, research proposal, and no less than one supporting letter from their supervising supervisor or Principal Investigator. Announcements of Awards can be made during Bay Area Lyme Foundation’s annual LymeAid® fundraising occasion in Might 2019. The complete standards and software for this award may be found at www.bayarealyme.org/our-research/emerging-leader-award.

About Bay Area Lyme Foundation Emerging Leader Awards
The Emerging Leader Awards from Bay Area Lyme Foundation are made potential annually by generous donations from the LaureL STEM Fund and the Steven & Alexandra Cohen Basis. These awards are introduced yearly and are designed to be awarded to promising scientists who have recognized an outlined strategy to improved diagnostics or therapies for Lyme disease. Researchers inquisitive about applying for the 2019 Emerging Leader Award or studying about the different grants that Bay Area Lyme Foundation gives all through the yr ought to contact [email protected]

About Lyme illness
Considered one of the commonest infectious illnesses in the country, Lyme illness is a probably disabling infection brought on by bacteria transmitted by way of the chew of an contaminated tick to individuals and pets. If caught early, most instances of Lyme disease may be effectively treated, but it is commonly misdiagnosed as a result of ignorance and unreliable diagnostic checks. There are about 329,000 new instances of Lyme disease annually, based on statistics launched in 2015 by the CDC. And, this number is rising yearly as 427,430 new Lyme instances are believed to have occurred in the US alone in 2017. Because of the problem in diagnosing and treating Lyme disease, as many as one million People may be suffering from the impression of its debilitating long-term symptoms and problems, in response to Bay Area Lyme Foundation estimates.

About Bay Area Lyme Basis
Bay Area Lyme Foundation, a national group committed to creating Lyme disease straightforward to diagnose and simple to remedy, is the main public not-for-profit sponsor of progressive Lyme disease analysis in the US. A 501c3 non-profit group based mostly in Silicon Valley, Bay Area Lyme Basis collaborates with world-class scientists and institutions to accelerate medical breakthroughs for Lyme disease. It’s also devoted to offering reliable, fact-based info so that prevention and the significance of early remedy are widespread information. A pivotal donation from The LaureL Basis covers overhead costs and allows for 100% of all donor contributions to Bay Area Lyme Basis to go on to research and prevention packages. For more details about Lyme disease or to become involved, visit www.bayarealyme.org or name us at 650-530-2439.