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Lyme Disease Biobank Expands to Increase Understanding of Lyme Disease in Heart, Brain, Joints and Other Tissues


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Tara DiMilia, 908-947-0500, [email protected]

Lyme Disease Biobank Expands to Increase Understanding of Lyme Disease in Coronary heart, Brain, Joints and Other Tissues

First-of-its-kind Biobank now accepts tissue donations from patients undergoing knee-replacements and comparable surgical procedures, in addition to patients who die with Lyme disease

Portola Valley, Calif., November 1, 2018 – Bay Space Lyme Foundation, a nationwide group funding analysis to make Lyme disease straightforward to diagnose and easy to remedy, declares the addition of the Lyme Disease Tissue Assortment Program to its Lyme Disease Biobank, which at present accepts blood samples. The enlargement of the Biobank will permit for a higher understanding of the power of Lyme bacteria to invade tissues and organs. The Lyme Disease Biobank is the only nationwide entity working to speed up research by accumulating surgical and post-mortem tissue samples from people with persistent Lyme illness and other tick-borne infections.

“While we, as clinicians, see patients who have symptoms of internal organ dysfunction such as heart and brain issues because of Lyme disease, it is frustrating that we don’t have the research to truly understand what’s going on, or how to better diagnose and treat these patients,” stated John Aucott MD, Associate Professor, Johns Hopkins College.

This system will dramatically improve the quantity of well-characterized tissue samples to allow research efforts to accelerate medical breakthroughs in the understanding, analysis and remedy of Lyme disease and other tick-borne infections.

“Many of my Lyme patients have had knee replacements and other joint surgeries, which may be related to their Lyme disease. By donating tissue, they can help empower and arm researchers with the tools they need to find more answers,” added Dr. Aucott.

While it’s not often potential to consider coronary heart and different organs of dwelling humans, a current pre-clinical research carried out out of Tulane College and funded by Bay Space Lyme Foundation, demonstrates that organs may be contaminated even when antibody checks are adverse. The research found multiple Lyme bacteria in the mind tissue of primate topics who had been handled with doxycycline, as well as in the guts, joints, bladder, skeletal muscle and adjacent to peripheral nerves of other subjects. It will be important for researchers to have the ability to discover if the identical factor is occurring to our human sufferers.

“We have patients eager to give what they can so that research can find answers for them and others, and researchers are in great need of qualified tissues to help them better understand this disease,” stated Liz Horn, PhD, MBI, principal investigator, Lyme Disease Biobank, a challenge of Bay Area Lyme Basis. “The addition of tissue samples to the Lyme Disease Biobank brings together these two desires, allowing patient donations to be properly screened and qualified so that the Lyme disease research community can utilize these much-needed biomedical resources essential for their work.”

The Lyme Disease Tissue Assortment Program also aims to acquire in depth medical info from donors, resembling signs, demographics, medical and social historical past, and historical past of Lyme disease and other tick-borne infections. If donors elect to enroll in the MyLymeData Affected person Registry, they will connect their MyLymeData profile with their tissue pattern. By pairing top quality tissue samples with strong medical knowledge, researchers can additional look at patients’ medical histories to understand and discover how the bacteria that causes Lyme invade the body, causing symptoms that have an effect on the joints, and the nervous and cardiovascular techniques.

“The expansion of the Lyme Disease Biobank is such an exciting step toward understanding how and why tick-borne diseases affect people the way they do,” stated Alexandra Cohen, president, Steven & Alexandra Cohen Foundation, whose beneficiant donation helped usher the Biobank into reality. “As someone who has lived with Lyme disease for nearly a decade, I am hopeful researchers—now with access to tissue—will make discoveries that lead to new treatments for all sufferers.”

The Lyme Disease Tissue Collection Program is a collaborative initiative comprised of the Lyme Disease Biobank, National Disease Analysis Interchange (NDRI) and MyLymeData Patient Registry. Individuals with Lyme disease interested in donating tissue are inspired to contact NDRI to register for the Dwelling Donor Registry. Collaborating individuals have to be 18 years of age or older, reside in the continental US, and be recognized with Lyme illness by a healthcare provider. Registered donors will complete an authorization and eligibility screening prior to donating tissue. If a registrant has a surgical procedure that removes tissue from an organ or joint, comparable to knee alternative, the harvested tissue could be donated to this research program. Sufferers who’re registered also can elect to have their essential organs donated for analysis after their passing.

This tissue program builds on the Lyme Disease Biobank’s blood sample collection effort to gasoline improved diagnostic exams for Lyme Disease. Presently, there are blood samples obtainable from more than 435 individuals, and each participant’s donation supplies samples for ~50 analysis tasks. Up to now, greater than 30 analysis tasks have used or are using samples from the Lyme Disease Biobank.

About Lyme Disease Tissue Assortment
The newly-launched Lyme Disease Tissue Collection Program is the one biobank amassing tissue samples for Lyme illness. As part of the Lyme Disease Biobank (LDB), which began in 2015, the program is amassing human organic samples, including approved tissues, resembling mind, musculoskeletal tissue, or coronary heart, from both surgical and/or autopsy individuals with persistent Lyme illness or different tick-borne infections. The program is being completed in collaboration with the Nationwide Disease Research Interchange (NDRI) and, a challenge of The LDB is a Sort I supporting group of Bay Space Lyme Basis.

Potential donors can register for the Lyme Disease Biobank on-line by way of NDRI’s Personal Donor Program ( or by calling NDRI at 800-222-NDRI (6374), Choice 5. Researchers in obtaining samples should visit [email protected]

About Lyme Disease
One of the most typical infectious illnesses in the country, Lyme disease is a probably disabling infection brought on by micro organism transmitted via the chew of an infected tick to individuals and pets. If caught early, most instances of Lyme illness might be successfully treated, however it is generally misdiagnosed due to lack of consciousness and unreliable diagnostic exams. There are about 329,000 new instances of Lyme disease annually, in accordance to statistics released in 2015 by the CDC. In consequence of the problem in diagnosing and treating Lyme illness, as many as one million People could also be suffering from the impression of its debilitating long-term symptoms and problems, in accordance to Bay Area Lyme Basis estimates.

About Bay Space Lyme Foundation
Bay Area Lyme Foundation, a national organization committed to making Lyme disease straightforward to diagnose and simple to remedy, is the main public not-for-profit sponsor of progressive Lyme illness research in the US. A 501c3 non-profit group based mostly in Silicon Valley, Bay Area Lyme collaborates with world-class scientists and institutions to speed up medical breakthroughs for Lyme illness. Additionally it is dedicated to offering dependable, fact-based info so that prevention and the significance of early remedy are widespread information. A pivotal donation from The Laurel Foundation covers all overhead prices and allows for 100% of all donor contributions to Bay Space Lyme Basis to go instantly to analysis and prevention packages. For extra information about Lyme illness or to become involved, visit or call us at 650-530-2439.

About MyLymeData
MyLymeData is a affected person registry and research platform that was developed and launched by Over 11,000 patients have enrolled in the registry, which uses huge knowledge research tools to permit patients to pool their knowledge shortly and privately to help discover a remedy. Patients interested in enrolling in the MyLymeData Patient Registry ought to go to

About NDRI
The National Disease Research Interchange (NDRI) is the nation’s main source of human tissues, cells and organs for scientific analysis. A not-for-profit 501 (c) (3) group based in 1980, NDRI is funded in part by the Nationwide Institutes of Well being, public and personal foundations and organizations, pharmaceutical and biotechnology firms. NDRI is a 24/7 operation that partners with a nationwide community of over 130 tissue source sites (TSS), including organ procurement organizations (OPOs), tissue banks, eye banks, and hospitals. The TSS, are distributed all through the USA, in 45 states, with concentrations in major metropolitan areas on both the east and west coasts. Their extensive geographic distribution permits NDRI to present biospecimens from donor populations with numerous demographics and also facilitates the timely and efficient provision of recent tissues immediately to researchers throughout the U.S. and all over the world. By serving because the liaison between procurement sources and the analysis group, NDRI is uniquely positioned to help breakthrough advances and discoveries that may have an effect on advances in the remedy and remedy of human illnesses.  For extra information about NDRI, go to, or name us at 800-222-NDRI.

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